A very common topic, S62 longevity. I could write a book about this, but I’ll try not to. Firstly… I am no expert. I’m just an owner of an E39 M5 for a little over 7 years, and 55,000 miles now. I am fairly active in the community though, so I do feel that I can talk about this some.
The S62 can last 300,000 miles. The S62 can also fail at 40,000 miles. There seem to be many more instances of higher miles than lower, however. These are the primary weak points of the S62: